Posted: January 29th, 2023

Cardiovascular and Renal Systems Diseases

NUR 7560 Advanced Pharmacology Cardiovascular and Renal Systems Diseases, Hypertension and the Integumentary and Dermatologic Systems

Unit 5: Cardiovascular and Renal Systems Diseases, Hypertension and the Integumentary and Dermatologic Systems

Welcome to Unit 5
Welcome to week five of Advanced Pharmacology. Drugs affecting the cardiovascular and renal systems are the focus of this week. The two systems are related physiologically, which is why they are covered in tandem. NUR 7560 Advanced Pharmacology Cardiovascular and Renal Systems Diseases, Hypertension and the Integumentary and Dermatologic Systems
Your heart is the center of your circulatory system. To fully comprehend the drugs affecting these systems, you will need to apply the pathophysiology you learned in your prior course. Understanding cardiac functional, electrical stimulation, cardiac potential, and mechanisms to maintain blood pressure are critical.
You will also need to be knowledgeable in homeostasis as an underlying principle to rational drug selection. The Renin-angiotensin system is of high importance in the regulation of homeostasis. Using your pathophysiology knowledge of the renal system and fluid volume will help to guide rational drug selection in addition to the topics in previous weeks of this course.
Additionally, this week will include the integumentary and dermatological systems. While many medications are topical, there are also systemic treatments. The themes for the unit include the ongoing importance of rational drug selection based on the presentation symptoms.
This week is foundational to your knowledge base, so please spend the time to connect your prior learning and catch up on anything you missed or review previous content and how that might impact rational drug selection for these systems.

Unit Learning Objectives

  • Examine the principles of pathophysiology and therapeutics that direct the pharmacotherapeutic interventions for Cardiovascular and Renal Systems Diseases, Hypertension and the Integumentary and Dermatologic Systems (CLO 1)
  • Analyze the pharmacokinetic and pharmacodynamic actions of agents used for management of Cardiovascular and Renal Systems Diseases, Hypertension and the Integumentary and Dermatologic Systems (CLO 2) NUR 7560 Advanced Pharmacology Cardiovascular and Renal Systems Diseases, Hypertension and the Integumentary and Dermatologic Systems
  • Apply the evidence for pharmacotherapeutic interventions in a patient with a Cardiovascular and Renal Systems Diseases, Hypertension and the Integumentary and Dermatologic Systems (CLO 1, 2)
  • Apply critical-thinking processes to the management and evaluation of expected effects and potential adverse effects of pharmacodynamic agents affecting Cardiovascular and Renal Systems Diseases, Hypertension and the Integumentary and Dermatologic Systems(CLO 1, 2, 3)
  • Evaluate the impact of pharmacogenomics, access, cost, quality, and safety on prescribing for Drugs Affecting Cardiovascular and Renal Systems Diseases, Hypertension and the Integumentary and Dermatologic Systems(CLO 4)
  • Examine the significance of interprofessional collaboration on patient outcomes (CLO 5)
  • Learning Materials

    Textbook
    • Woo, T. M., & Robinson, M., V. (2020). Pharmacotherapeutics for advanced practice nurse prescribers (5th ed.). F. A. Davis.
      • Chapter 13: Drugs Affecting the Cardiovascular and Renal Systems
      • Chapter 22: Drugs Affecting the Integumentary System
      • Chapter 34: Dermatological Conditions
      • Chapter 42: Hypertension
    Textbook PowerPoint
    • Woo, T. M., & Robinson, M., V. (2020). Pharmacotherapeutics for advanced practice nurse prescribers (5th ed.). F. A. Davis.
      •  Chapter 13: Drugs Affecting the Cardiovascular and Renal Systems
      •  Chapter 22: Drugs Affecting the Integumentary System
      •  Chapter 34: Dermatological Conditions
      •  Chapter 42: Hypertension
    Faculty Lectures
    • Dunlap, J. (2021). NUR 7560  Chapter 13 – Drugs Affecting the Cardiovascular and Renal Systems Part I.ppsx
    • Dunlap, J. (2021). NUR 7560  Chapter 13 – Drugs Affecting the Cardiovascular and Renal Systems Part I NonRecorded.pptx
    • Dunlap, J. (2021). NUR 7560  Chapter 13 – Drugs Affecting the Cardiovascular and Renal Systems Part II.ppsx
    • Dunlap, J. (2021). NUR 7560  Chapter 13 – Drugs Affecting the Cardiovascular and Renal Systems Part II NonRecorded.pptx
    Unit 5 Optional Learning Resources:
    Media

    Faculty Lecture: Drugs Affecting the Cardiovascular and Renal Systems – Part I

    Faculty Lecture: Drugs Affecting Cardiovascular and Renal Systems – Part II

    Unit 5 and 6 Combined Concept Map

    The purpose of this combined Unit 5 and 6 Concept Map is to understand cardiac and renal function, electrical stimulation, cardiac potential, and mechanisms to maintain blood pressure. Additionally, the integumentary and dermatological systems review pharmacological managements of various disorders. NUR 7560 Advanced Pharmacology Cardiovascular and Renal Systems Diseases, Hypertension and the Integumentary and Dermatologic Systems In Unit 6 the intricacies of the Respiratory, Hematopoietic and Immune systems, and Anemias are analyzed. You will also need to understand and apply homeostasis as an underling principle to rational drug selection. This Assignment is intended to allow you to show evidence of achieving the following Course Learning Outcome(s):
    • CLO 1: Apply critical thinking and best scientific evidence to the management and evaluation of expected effects, potential adverse effects, and potential interactions of pharmacological agents for the treatment of self-limiting acute conditions and chronic diseases across the lifespan (MSN PLO 7) (ILO 1,5) (MSN Essential I)
    • CLO 2: Analyze the pharmacodynamics and the pharmacokinetic impact of pharmacologic therapies in the treatment of diseases and altered states. (MSN PLO 1,7) (ILO 1,5) (MSN Essential I)
    • CLO 3: Formulate therapeutic regimens for patients, including patients with altered pharmacodynamics and pharmacokinetics special populations, such as infants and children, pregnant and lactating women, and older adults with using cultural competence. (MSN PLO 7) (ILO 1) (MSN Essential VIII)
    • CLO 4: Evaluate the impact of pharmacogenomics, access, cost, quality, and safety on prescribing. (MSN PLO 5) (ILO 1) (MSN Essential III)
    • CLO 5: Examine the significance of interprofessional collaboration on patient outcomes. (MSN PLO 6) (ILO 4) (MSN Essential VIII)
    To prepare for this Assignment, read the assigned chapters and review the PowerPoint slides.
    To complete this Assignment: Concept Map Development Information. The following is a link that reviews the creation of a concept map: https://owl.excelsior.edu/orc/what-to-do-after-reading/analyzing/creating-a-concept-map/
    Additional video that may be helpful: https://www.youtube.com/watch?v=OGAukeDMzEY
    Concept Map Assignment directions:
    This Assignment consists of three parts:
    Part 1:
    • Develop a concept map which is a visual representation of interrelated concepts, or processes including a class of pharmacological therapy. This should be in word or PDF format. You are encouraged to use different shapes/colors for the different components required. Please choose one drug class from Unit 5 or Unit 6 and develop the following:
    • Pharmacokinetics
    • Pharmacodynamics
    • Pharmacoeconomic considerations
    • Common Drugs in this drug class
    • Clinical considerations such as indications, contraindications, dosage of a key drug from the class including various ages (ie: geriatric), metabolism, adverse effects and drug/herbal interactions NUR 7560 Advanced Pharmacology Cardiovascular and Renal Systems Diseases, Hypertension and the Integumentary and Dermatologic Systems
    • Link to an appropriate Clinical Practice Guideline (include link in a box for the concept map)
    • Collaborative Management – what other disciplines may be involved in the care of this patient group and why?
    Paper Format:
    • There should be a title page, reference page and your concept map in the middle.
    • Use appropriate APA format.
    • Include a minimum of 3 scholarly, peer reviewed, timely research articles to support the content of the concept map
    • Web sites used should be noncommercial (e.g., gov, edu, org) websites
    Part 2 (Due Monday of Week 6):
    • You will submit a Kaltura video of yourself presenting the concept map and describing your rationale for each element. This should be brief, but you should speak slowly and clearly and be fully able to explain the concepts.
    • The concept map should be visible
    • You should be visible
    • It should be no longer than 5 minutes in length. See rubric for grading components of Kaltura video.
    • Submit the Kaltura video to the discussion board for your peers to review.
    Part 3 (Due Sunday of Week 6):
    • In the discussion area, respond to at least one peer who completed a different topic than yours
    • Include at least 1 scholarly, peer reviewed research article to support your input
    • Response post must be at least 100 words excluding salutation and references.
    Due Dates:
    • Initial paper submission including Concept Map Due by Day 5 (Friday) of Week 5
    • Kaltura Video posted to discussion board by Due by Day 1 (Monday) of Week 6
    • Response to at least 1 peer Due by Day 7 (Sunday) of Week 6
  • Unit Conclusion

    As we wrap up week five of Advanced Pharmacology, we learn the cardiovascular and renal systems are related physiologically. Understanding homeostasis as an underlying principle to rational drug selection will continue to be critical. Understanding your pathophysiology knowledge will help to guide rational drug selection in all topics in this course.
    Next week, we continue our systems focus, and explore respiratory, integumentary and dermatologic systems.

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