Posted: October 17th, 2017
Methotrexate is a folate antagonist. It inhibits enzymes required for DNA base synthesis. To prevent harm to normal cells, a fully activated form of folic acid known as leucovorin (folinic acid; citrovorum factor) can be administered. Administration of leucovorin is known as:
A. Induction therapy.
B. Consolidation therapy.
C. Pulse therapy.
D. Rescue therapy.
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