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Posted: January 29th, 2023

Drugs Affecting the Central Nervous System, Pain Management, Alcohol and Drug Addiction

Drugs Affecting the Central Nervous System, Pain Management, Alcohol and Drug Addiction

Unit 4: Drugs Affecting the Central Nervous System, Pain Management, Alcohol and Drug Addiction

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    Introduction: Drugs Affecting the Central Nervous System, Pain Management, Alcohol and Drug Addiction

    Welcome to Unit 4

    Drugs that affect the central nervous system can be broadly categorized into those used to treat psychiatric or neurological conditions. These drugs affect neuroreceptors and neurotransmitters, in different parts of the brain, to bring a response Drugs Affecting the Central Nervous System, Pain Management, Alcohol and Drug Addiction. Like the previous week, understanding the central nervous system will have a critical impact on rational drug selection and side effect management. So please spend ample time in this area.
    Pain management, both acute and chronic, are topics of national concern, due to high rates of controlled substance abuse. The treatment plan is guided by the history, intensity, duration, aggravating and relieving conditions, and structures involved in causing the pain. In this course, we will focus on the pharmacology and the goals of treatment, along with rational drug selection, keeping in mind a safe and effective treatment plan.
    Another key area of practice will be managing alcohol and drug addiction. Knowing the signs that indicate a possible addiction and possible treatment to assist the patient in recovery are a key component of the NP role.

    Unit Learning Objectives

    • Examine the principles of pathophysiology and therapeutics that direct the pharmacotherapeutic interventions affecting the central nervous system, as well as pain management and Alcohol/drug addiction (CLO 1)
    • Analyze the pharmacokinetic and pharmacodynamic actions of agents affecting the central nervous system, as well as pain management and Alcohol/drug addiction (CLO 2)
    • Apply critical-thinking processes to the management and evaluation of expected effects, potential adverse effects, and potential interactions of pharmacological agents affecting the central nervous system, as well as pain management and Alcohol/drug addiction (CLO 3)
    • Apply critical-thinking processes to the management and evaluation of expected effects, potential adverse effects, and potential interactions of pharmacological agents affecting pain management and Alcohol/Drug addiction (CLO 1,2,3)
    • Evaluate the impact of pharmacogenomics, access, cost, quality, and safety on prescribing forDrugs Affecting the Central Nervous System, Pain Management, Alcohol and Drug Addiction (CLO 4)
    • Examine the significance of interprofessional collaboration on patient outcomes (CLO 5)
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    Learning Materials

    Textbook
    • Woo, T. M., & Robinson, M., V. (2020). Pharmacotherapeutics for advanced practice nurse prescribers (5th ed.).F. A. Davis.
      • Chapter 12: Drugs Affecting the Central Nervous System
      • Chapter 27: Alcohol and Drug Addiction
      • Chapter 44: Pain Management: Acute and Chronic Pain
    Textbook PowerPoints
    • Woo, T. M., & Robinson, M., V. (2020). Pharmacotherapeutics for advanced practice nurse prescribers (5th ed.). F. A. Davis.
      •  Chapter 12: Drugs Affecting the Central Nervous System
      •  Chapter 27: Alcohol and Drug Addiction
      •  Chapter 44: Pain Management: Acute and Chronic Pain
    Faculty Lectures
    • Dunlap, J. (2021).  Chapter 27 – Alcohol Benzos.ppsx
    • Dunlap, J. (2021).  Chapter 27 – Alcohol Benzos NonRecorded.pptx
    • Dunlap, J. (2021).  Chapter 27 – Opiates.ppsx
    • Dunlap, J. (2021).  Chapter 27 – Opiates NonRecorded.pptx
    Unit 4 Optional Learning Resources:
    Media
    • Osmosis. (2017, March 6). Alcoholism – causes, symptoms, diagnosis, treatment, pathology [Video]. YouTube. https://www.youtube.com/watch?v=e5DxD6Tuxxw
    • Speed Pharmacology. (2018, July 17). Pharmacology – Antipsychotics (made easy) [Video]. YouTube. https://www.youtube.com/watch?v=nKkIh1B2Js8
    • Speed Pharmacology. (2017, December 7). Pharmacology – NSAIDs & prostaglandin analogs (made easy) [Video]. YouTube. https://www.youtube.com/watch?v=I1uHkbocRCw
    • Speed Pharmacology. (2018, September 2017). Pharmacology – benzodiazepines, barbiturates, hypnotics (made easy) [Video]. YouTube. https://www.youtube.com/watch?v=4ZHudeMho8g
    • Speed Pharmacology. (2018, November 5). Antiepileptic drugs (made easy) [Video]. YouTube. https://www.youtube.com/watch?v=xFUHE9gX6W8
    • Speed Pharmacology. (2019, January 28). Opioids (made easy) [Video]. YouTube. https://www.youtube.com/watch?v=t2tKyjj7u5Y
    Websites
    • International Union of Basic and Clinical Pharmacology. (n.d.). Nervous system. Pharmacology Education Project. Retrieved November 17, 2021, from https://www.pharmacologyeducation.org/drugs/nervous-system
      • Click the above link for both a narrative summary as well as short education videos on the nervous system.
    • Khan Academy. (2018f). Advanced nervous system physiology. Retrieved March 11, 2021, from https://www.khanacademy.org/science/health-and-medicine/nervous-system-and-sensory-infor
    • Khan Academy. (2018r). Nervous system diseases. Retrieved March 11, 2021, from https://www.khanacademy.org/science/health-and-medicine/nervous-system-diseases
    • Omineca Medical Clinic. (2016). Algorithm for initiating antidepressant therapy in depression. Retrieved March 11, 2021, from http://www.ominecamedicalclinic.com/pdf/ANTIDEPRESSANT%20THERAPY%20ALGORITHM.pdf
    • University of Florida Health. (2020). Pain management and dosing guide. Retrieved March 11, 2021, from https://pami.emergency.med.jax.ufl.edu/resources/dosing-guide/#:~:text=The%20PAMI%20Pain%20Management%20and%20Dosing%20Guide%20is,chronic%20pain%20and%20procedural%20sedation%20in%20all%20ages.
    • U.S. Department of Health and Human Services, Centers for Disease Control and Prevention. (2017a). CDC guideline for prescribing opioids for chronic pain. https://www.cdc.gov/drugoverdose/prescribing/guideline.html
    • U.S. Department of Health and Human Services, Centers for Disease Control and Prevention. (2017b). Training for providers. Retrieved March 11, 2021, from https://www.cdc.gov/drugoverdose/training/index.html
    • U.S. Department of Health and Human Services, U.S. Food & Drug Administration. (2017b). Training health care providers on pain management and safe use of opioid analgesics – Exploring the path forward. Retrieved March 11, 2021, Drugs Affecting the Central Nervous System, Pain Management, Alcohol and Drug Addiction from https://www.fda.gov/Drugs/NewsEvents/ucm538047.htm
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    Faculty Lecture: Alcohol and Drug Addiction – Alcohol and Benzos

    Attached Files:
    • File Alcohol and Drug Addiction – Alcohol and Benzos Transcript.pdf (38.078 KB)
    • File Alcohol and Drug Addiction – Alcohol and Benzos Handout.pdf (18.609 MB)
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    Faculty Lecture: Alcohol and Drug Addiction – Opiates Drugs Affecting the Central Nervous System, Pain Management, Alcohol and Drug Addiction

    Attached Files:
    • File Alcohol and Drug Addiction – Opiates Transcript.pdf (44.264 KB)
    • File Alcohol and Drug Addiction – Opiates Handout.pdf (19.68 MB)
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    Unit 3 and 4 Case Study

    See Submission Link in Unit 3
  • Assignment

    Unit 4: CDC Module #5

    To prepare you for your future practice and management of patient pain and inquiry into possible opioid use disorder.This assignment is intended to allow you to show evidence of achieving the following Course Learning Outcomes (CLO):
    • CLO 1: Apply critical thinking and best scientific evidence to the management and evaluation of expected effects, potential adverse effects, and potential interactions of pharmacological agents for the treatment of self-limiting acute conditions and chronic diseases across the lifespan (MSN PLO 7) (ILO 1,5) (MSN Essential I)
    • CLO 2: Analyze the pharmacodynamics and the pharmacokinetic impact of pharmacologic therapies in the treatment of diseases and altered states. (MSN PLO 1,7) (ILO 1,5) (MSN Essential I)
    • CLO3: Formulate therapeutic regimens for patients, including patients with altered pharmacodynamics and pharmacokinetics special populations, such as infants and children, pregnant and lactating women, and older adults with using cultural competence. (MSN PLO 7) (ILO 1) (MSN Essential VIII)
    • CLO 4: Evaluate the impact of pharmacogenomics, access, cost, quality, and safety on prescribing. (MSN PLO 5) (ILO 1) (MSN Essential III) Drugs Affecting the Central Nervous System, Pain Management, Alcohol and Drug Addiction
         You must sign in to the account created in unit 1 at the CDC Training and Continuing Education Online to receive the Continuing Educaiton Certificate
    To further assist in your learning, complete the following CDC Module #5: Assessing and Addressing Opioid Use Disorder (https://www.cdc.gov/opioids/providers/training/assessing-addressing-oud.html)
    It may be helpful to also download a copy of the: CDC Guideline for Prescribing Opioids for Chronic Pain – United States, 2016
    Link: https://www.cdc.gov/mmwr/volumes/65/rr/rr6501e1.htm
    You will have the opportunity at the end of the module to obtain Continuing Education Credit. Please submit this certificate to the assignment link as proof of completion of the module and obtain credit for the assignment.
    Submit Completion Certificate/CE to Assignment link Due Date: Sunday of Week 4
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    Exam 1 Practice Quiz

    You will have unlimited access to the practice quiz throughout the term. It is 50 questions in length. This is not graded but for your practice and review. Drugs Affecting the Central Nervous System, Pain Management, Alcohol and Drug Addiction
    Exam 1 Practice Quiz Link
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    Exam 1: Study Guide

    7560 Ex 1 Study Guide_2022.1.docx
  • Test

    Unit 4: Exam 1 (**Webcam**) – Requires Respondus LockDown Browser

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    Unit Conclusion

    As we wrap up week four of advanced pharmacology, we learned about the drugs that affect the central nervous system, such as those used to treat psychiatric or neurological conditions. These drugs affect neuroreceptors and neurotransmitters in different parts of the brain to bring a response. This is not the last time you will learn about neurotransmitters or receptors, so keep this learning in mind as we proceed to the cardiovascular and renal systems.
    Always focus on the goals of treatment, along with rational drug selection, keeping in mind safe and effective treatment plan Drugs Affecting the Central Nervous System, Pain Management, Alcohol and Drug Addiction

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