Posted: September 7th, 2016

Compute the odds of miscarriage in women with heavy alcohol use during pregnancy.

A case-control study is conducted to assess the relationship between heavy alcohol use during the first trimester of pregnancy and miscarriage. Fifty women who suffered miscarriage are enrolled, along with 50 who delivered full-term. Each participant’s use of alcohol during pregnancy is ascertained. Heavy drinking is defined as four or more drinks on one occasion. The data are shown in Table 3–10.
• a. Compute the odds of miscarriage in women with heavy alcohol use during pregnancy.
• b. Compute the odds of miscarriage in women with no heavy alcohol use during pregnancy.
TABLE 3–9 Hypertension at Baseline and Stroke Five Years Later
Free of Stroke at Five Years Stroke
Baseline: Not
hypertensive 952 46
Baseline: Hypertensive 234 18
TABLE 3–10 Alcohol Use and Outcome of Pregnancy
Miscarriage Delivered Full Term
Heavy alcohol use 14 4
No heavy alcohol use 36 46
• c. Compute the odds ratio for miscarriage as a function of heavy alcohol use.