Posted: September 7th, 2016

Compute the cumulative incidence of hypertension over two years.

A cohort study is conducted to assess the association between clinical characteristics and the risk of stroke. The study involves n = 1250 participants who are free of stroke at the study start. Each participant is assessed at study start (baseline) and every year thereafter for five years. Table 3–8 displays data on hypertension status measured at baseline and hypertension status measured two years later.
TABLE 3–8 Hypertension at Baseline and Two Years later
Two Years Later: Not Hypertensive Two Years Later: Hypertensive
Baseline: Not
hypertensive 850 148
Baseline:
hypertensive 45 207
• a. Compute the prevalence of hypertension at baseline.
• b. Compute the prevalence of hypertension at two years.
• c. Compute the cumulative incidence of hypertension over two years.
2.
The data shown in Table 3–9 were collected in the study described in Problem 1 relating hypertensive status measured at baseline to incident stroke over five years.
• a. Compute the cumulative incidence of stroke in this study.
• b. Compute the cumulative incidence of stroke in patients classified as hypertensive at baseline.
• c. Compute the cumulative incidence of stroke in patients free of hypertension at baseline.
• d. Compute the risk difference of stroke in patients with hypertension as compared to patients free of hypertension.
• e. Compute the relative risk of stroke in patients with hypertension as compared to patients free of hypertension.
• f. Compute the population attributable risk of stroke due to hypertension.